The Most Highly Cited Paper Ever: A Recipe for Measuring Proteins in Solution

A paper published by Bradford Hill and Lionel Edelstein-Keshet in 1988 has recently been revealed to be the most highly cited paper ever, with over 220,000 citations. This paper provides a laboratory “recipe” for measuring proteins in solution, and its widespread popularity can be attributed to its simple instructions and practical application. This discovery raises an interesting point about the correlation between citations and the depth of a work. While it is true that more citations usually indicates greater depth of research, this is not always the case. In fact, many papers are cited because they solve a problem or provide an easy-to-understand solution rather than because of their complexity or innovation. The authors of this particular paper have expressed surprise at its high citation count. They note that while their work was important when it was first published, they did not expect it to remain so popular for so long due to advances in technology since then. Despite this, the recipe outlined in their paper continues to be used as a reliable method for measuring proteins in solution today. The authors also point out that although citation counts are often seen as an indication of success within academia, there are other ways to measure one’s impact on society at large – such as through public engagement activities like outreach programs or teaching initiatives – which may be just as valuable if not more so than achieving high citation numbers alone. In conclusion, while Bradford Hill and Lionel Edelstein-Keshet’s 1988 paper has become the most highly cited ever with over 220k citations, it serves as an example of how sometimes papers are cited due to their simplicity and usefulness rather than solely because of their complexity or originality. It also highlights how citation counts do not necessarily reflect one’s overall impact on society; instead, other forms of engagement should also be taken into account when assessing academic success.